李伟,女,1984年出生,山东聊城人,博士,副研究员,硕士生导师,获“珠江新星”称号。
现任水产种质资源与遗传育种研究室副主任,中国水产科学研究院“龟鳖遗传育种创新团队”首席,长期从事水产动物种质资源与遗传育种的研究工作。兼任“第九届广东省海洋湖沼学会”、“第八届广东海洋学会”理事,中国水产流通与加工协会“龟鳖行业专家技术委员会”委员,上海海洋大学、西南大学、长江大学、江苏海洋大学、河南师范大学、福建农林大学、新疆农业大学及天津农学院等高校的硕士生导师。
主持国家自然科学基金、国家重点研发计划水产生物育种共性前沿技术创新青年科学家项目(子课题)、农业基础性长期性科技工作国家渔业科学数据中心观测监测任务、广东省自然科学基金面上项目、广州市科技计划科技创新人才专项、中国水产科学研究院院级基本科研业务费等项目共20余项。作为主完成人,获新品种1个;获得成果奖励2项;发表论文60余篇(第一作者/通讯作者21篇);授权发明专利20余项(第一发明人8项)、实用新型专利10余项(第一发明人1项);参编著作1部。
联系方式:
1)联系电话:15013083966
2)E-mail:664061430@qq.com
3)通讯地址:广州市荔湾区芳村西朗兴渔路1号
研究方向:水产种质资源与遗传育种
主持的重点项目(列举重大项目5项)
1)国家重点研发计划“海洋农业与淡水渔业科技创新”重点专项-水产生物育种共性前沿技术创新青年科学家项目(子课题):水产养殖动物育性控制技术研究,2022/11-2026/12。
2)国家自然科学基金-青年科学基金项目:Ran基因对中华鳖雌性性别分化的调控作用及机制研究,2022/01-2024/12。
3)广东省自然科学基金-面上项目:中华鳖性别特异性标记的鉴定及分子遗传特征解析,2018/05-2022/04。
4)广州市科技计划科技创新人才专项“珠江科技新星”项目:中华鳖性别分化关键基因的筛选及功能鉴定,2018/04-2021/03。
5)农业基础性长期性科技工作国家渔业科学数据中心观测监测任务:珠江水系土著鱼种生物多样性评价,2017/05 -2019/12。
代表论文与著作(限第1作者及通讯作者)
1)Junxian Zhu Yongchang Wang, Luo Lei, Chen Chen, Liqin Ji, Jiansong Li, Congcong Wu, Wenjun Yu, Laifu Luo, Weiqin Chen, Pan Liu, Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu*, andWei Li*, Comparative genomic survey and functional analysis ofDKKL1during spermatogenesis in the Chinese soft-shelled turtle (Pelodiscus sinensis). Int J Biol Macromol. 2024, 30:127696. doi: 10.1016/j.ijbiomac.2023.127696(IF2022=8.2,中科院一区)
2)Junxian Zhu, Yongchang Wang, Chen Chen, Liqin Ji,Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu*, andWei Li*, Identification of sex-specific markers and candidate genes using WGS sequencing reveals a ZW-type sex-determination system in the Chinese soft-shell turtle (Pelodiscus sinensis). International Journal of Molecular Sciences. 2024, 25, 819.(IF2022=5.60,JCR一区)
3)Yongchang Wang, Junxian Zhu, Chen Chen, Liqin Ji, Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu, Junjie Zhang*, andWei Li*, Whole-Genome Identification and Characterization of the DKK Gene Family and Its Transcription Profiles: An Analysis of the Chinese Soft-Shell Turtle (Pelodiscus sinensis). Animals, 2024, 14(6): 931. doi: 10.3390/ani14060931. (IF2022=3.0, JCR一区)
4)Junxian Zhu, Luo Lei, Chen Chen, Jiansong Li, Yongchang Wang, Congcong Wu, Yakun Wang, Xiaoyou Hong, Xiaoli Liu, Lingyun Yu, Haigang Chen, Chengqing Wei, Yihui Liu,Wei Li*, and Xinping Zhu*, Development and evaluation of a medium-free incubation method for hatching Chinese soft-shelled turtle (Pelodiscus sinensis) eggs. Aquacult Rep.2023, 31:2352-5134. doi: https://doi.org/10.1016/ j.aqrep.2023.101643. (IF2022=3.7, JCR一区)
5)Lei Luo, Zhu Junxian, Chen Chen, Wang Yongchang, Wu Congcong, Qi Ming,Wang Yakun, Liu Xiaoli, Hong Xiaoyou, Yu Lingyun, Chen Haigang, Wei Chengqing,Liu Yihui,Li Wei*and Zhu Xinping*, Genome-wide identification, evolution and expression analysis of bone morphogenetic protein (BMP) gene family in chinese soft-shell turtle (Pelodiscus sinensis). Front. Genet. 2023, 14:1109478.doi: 10.3389/fgene.2023.1109478(IF2022=3.7, JCR一区)
6)Junxian Zhu#, Luo Lei#, Chen Chen, Yakun Wang, Xiaoli Liu, Lulu Geng, Ruiyang Li, Haigang Chen, Xiaoyou Hong, Lingyun Yu, Chengqing Wei,Wei Li*, Xinping Zhu*. Whole-Transcriptome Analysis Identifies Gender Dimorphic Expressions of Mrnas and Non-Coding Rnas in Chinese Soft-Shell Turtle (Pelodiscus sinensis). Biology. 2022, 11, 834. Doi.org/10.3390/biology11060834 (IF2021=5.168, JCR一区)
7)Luo Lei#, Junxian Zhu#, Chen Chen, Yakun Wang, Xiaoyou Hong, Xiaoli Liu, Lingyun Yu, Chengqing Wei, Haigang Chen, Yihui Liu, Ruiyang Li,Wei Li*, Xinping Zhu*, Expression and Characterization of the Spats1 Gene and Its Response to E2/MT Treatment in the Chinese Soft-Shelled Turtle(Pelodiscus sinensis). Animals. 2022, 12, 1858.https://doi.org/10.3390/(IF2021=3.231, JCR一区)
8)Luo Lei#, Chen Chen, Junxian Zhu, Yakun Wang, Xiaoli Liu, Haiyang Liu, Lulu Geng, Junyu Su,Wei Li*, Xinping Zhu*, Transcriptome analysis reveals key genes and pathways related to sex differentiation in the Chinese soft-shelled turtle (Pelodiscus sinensis). Comp Biochem Physiol Part D Genomics Proteomics.2022, 42: 100986.(IF2021=3.306, JCR三区)
9)Wei Li#,Junxian Zhu, Luo Lei, Chen Chen, Xiaoli Liu, Yakun Wang, Xiaoyou Hong, Lingyun Yu, Hongyan Xu*,Xinping Zhu*, The Seasonal and Stage-Specific Expression Patterns ofHMGB2Suggest Its Key Role in Spermatogenesis in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis).Biochemical Genetics, 2022: 1-14.(IF2021=2.220, JCR四区)
10)Wei Li#,Junxian Zhu, Chen Chen, Yakun Wang, Luo Lei, Lulu Geng, Junyu Su,Xinping Zhu*, Isolation and characterization of sex‐linked SNP markers from transcriptomic sequences of the Chinese soft‐shelled turtle (Pelodiscus sinensis). Conservation Genetics Resources, 2022: 1-6.(IF2021=0.991, JCR四区)
11)Wei Li#, Luo Lei, Junxian Zhu, Haigang Chen, Chen Chen, Yakun Wang, Lulu Geng, Fangcan Chen,Xinping Zhu*, Simple and rapid method for molecular identification ofKonosirus punctatusandClupanodon thrissa. Conservation Genetics Resources, 2022: 1-3.(IF2021=0.991, JCR四区)
12)Yakun Wang#, Xiaoli Liu, Lingyun Yu, Xiaoyou Hong, Jian Zhao, Junxian Zhu, Ju Yuan,Wei Li*,Xinping Zhu*,Identification and analysis of novel microRNAs provide insights to reproductive capacity of the cultured Asian yellow pond turtleMauremys mutica. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2021, 40: 100890.(IF2020=2.674, JCR三区)
13)Wei Li#,Piaoyi Zhang#, Xuling Wu, Xinping Zhu*, Hongyan Xu*, A Novel Dynamic Expression of vasa in Male Germ Cells during Spermatogenesis in the Chinese Soft-Shell Turtle (Pelidiscus sinensis), Journal of Experimental Zoology Part B Molecular & Developmental Evolution, 2017, 328(3):230-239.(IF2016=2.387, JCR一区)
14)Wei Li#, Xincheng Zhang, Jian Zhao, Yan Shi, Xinping Zhu*, Complete mitochondrial genome ofCuora trifasciata(Chinese three-striped box turtle), and a comparative analysis with other box turtles, Gene, 2015, 555(2): 169-77.(IF2015=2.319, JCR二区)
15)Wei Li#, Jian Zhao, Yan Shi, Feng-Fang Xiao, Xin-Cheng Zhang , Xin-Ping Zhu*,The complete mitochondrial genome of the critically endangered Vietnamese three-striped box turtle (Testudines: Geoemydidae).Mitochondrial Dna, 2015, 26(6):925(IF2015=1.76, JCR三区)
16)Liu Xiaoli#,Li Wei#,Ye Zhaoyang, Zhu Yanyu, Hong Xiaoyou,Zhu Xinping*. Morphological characterization and phylogenetic relationships of Indochinese box turtles—TheCuora galbinifronscomplex. Ecology and Evolution, 2019, 23(9): 13030-13042.(IF2018=2.415, JCR三区)
17)汪泳昌,祝骏贤,李建松,陈辰,纪利芹,洪孝友,刘晓莉,王亚坤,吴聪聪,余汶君,罗来福,陈海港,魏成清,朱新平,张俊杰*,李伟*.中华鳖Dkkl1基因的分子特征及对外源性激素处理的响应[J].南方水产科学, 2023.
18)雷骆,祝骏贤,陈辰,王亚坤,刘晓莉,洪孝友,于凌云,魏成清,李伟*,朱新平*.基于转录组测序的中华鳖SSR和SNP特征分析及性别标记筛选[J].广东海洋大学学报, 2023, 43(1): 44-49.
19)祝骏贤#,陈辰,刘晓莉,王亚坤,雷骆,洪孝友,于凌云,徐红艳,李伟*,朱新平*,中华鳖组蛋白H2A变体克隆及其在卵母细胞中的表达分析[J].水生生物学报, 2021, 45(6): 7.
20)李伟#,史燕,赵建,洪孝友,朱新平*,中华鳖转铁蛋白基因序列特征及表达研究,水生生物学报, 2015, 39(3): 482-489.
21)李伟#,朱阿莉,史燕,朱新平*,嗜水气单胞菌诱导的中华鳖smart cdna文库构建及相关基因的鉴定,基因组学与应用生物学, 2014, 33(4): 788-795.
授权专利(限第1发名人):
1)李伟,朱新平,雷洛,祝骏贤,陈辰,刘晓莉,洪孝友,纪利芹,汪永昌,鉴别绦虫Testudotaenia sp.WL-2016的分子标记及应用,国家发明专利,专利号:ZL202310232583.X,授权日期:2024.03.12
2)李伟,朱新平,祝骏贤,陈辰,洪孝友,刘晓莉,纪利芹,雷骆,汪永昌,一种中华鳖精子特异表达分子标记及其应用,国家发明专利,专利号:ZL202310860495.4,授权日期:2024.02.13.
3)李伟,祝骏贤,朱新平,雷骆,陈辰,王亚坤,陈海港,洪孝友,刘晓莉,于凌云,刘毅辉,魏成清,鉴别珍珠鳖性别的分子标记、引物对及其应用,国家发明专利,专利号:ZL202211412201.3,授权时间:2023.10.17.
4)李伟,雷骆,朱新平,祝骏贤,陈辰,王亚坤,陈海港,洪孝友,刘晓莉,于凌云,刘毅辉,魏成清,鉴别角鳖性别的分子标记、引物对及其应用,国家发明专利,专利号:ZL202211411167.8,授权时间:2023.07.04.
5)李伟,雷骆,朱新平,祝骏贤,陈辰,王亚坤,陈海港,洪孝友,刘晓莉,于凌云,刘毅辉,魏成清,鉴别山瑞鳖性别的分子标记、引物对及其应用,国家发明专利,专利号:ZL202211411732.0,授权时间:2023.08.01.
6)李伟,朱新平,雷骆,祝骏贤,陈辰,刘晓莉,洪孝友,纪利芹,汪永昌,一种中华鳖雌性特异Rab35基因及其应用,国家发明专利,专利号:ZL202310860496.9,授权时间:2023.12.12.
7)李伟,朱新平,徐红艳,赵建,陈辰,一种快速鉴定中华鳖遗传性别的PCR扩增引物、方法及试剂盒,国家发明专利,专利号:201810685968.0,授权时间:2020.05.05.
8)李伟,朱新平,雷骆,陈海港,一种基于线粒体COI基因鉴别花鰶和斑鰶的分子标记及其应用,国家发明专利,专利号:202011419113.7,授权时间:2021.07.03.
9)李伟,朱新平,刘海涌,陈辰,高柳玲,陈海港,陈强,刘毅辉,陈运新,王亚坤,洪孝友,刘晓莉,于凌云,魏成清,一种斑鳠养殖池塘越冬设备,实用新型专利,专利号:ZL202221900204.7,授权时间:2022.10.18.