刘晓莉,女,1988年生,博士,副研究员,入选中国水产科学研究院水科英才“拔尖人才”培育计划。上海海洋大学硕士生导师,院龟鳖遗传育种创新团队专业学术带头人,农业农村部热带亚热带水产资源利用与养殖重点实验室秘书,中国水产流通与加工协会龟鳖行业专家技术委员会委员。主要从事龟鳖动物生殖发育研究及种质挖掘与利用工作,先后主持国家自然科学基金青年项目、国家重点研发计划蓝色粮仓子课题、广东省自然科学基金面上项目等各类项目11项,作为技术骨干参与国家自然科学基金面上项目、广东省科技计划项目等20余项。以第一或通讯作者(含共同)在Scientific Data、Biology of Reproduction、Heredity、Frontiers in Cell and Developmental Biology等杂志发表学术论文20余篇,获钟麟水产种业科技奖1项(第8完成人),参编著作2部,授权专利10余件(第1发明人1件)。
联系方式:
(1)电话:18898410309,020-81174522
(2)邮箱:liu_xiaoli1988@126.com
(3)通讯地址:广东省广州市荔湾区芳村西朗兴渔路1号
研究方向:龟鳖动物生殖发育及种质挖掘与利用
主持的重点项目(列举重大项目5项):
1.国家自然科学基金青年项目:黄喉拟水龟cyp11b2基因在性别分化中的功能解析,2022.01-2024.12。
2.国家重点研发计划“蓝色粮仓科技创新”重点专项“水产养殖动物性别转换与环境因子的互作机制”子课题:2018.12-2022.12。
3.广东省自然科学基金面上项目:hsp90aa1在黄喉拟水龟雌性分化中的作用机制解析,2022.01-2024.12。
4.广东省区域联合基金-青年项目:Tdrd7基因在黄喉拟水龟雌性分化中的作用机制研究,2020.10-2023.09。
5.广州市科技计划项目:黄喉拟水龟性别调控相关基因甲基化模式与性别分化关联解析,2019.04-2022.03。
主要科技奖励:
中华鳖“珠水1号”新品种创制及配套养殖技术推广(第8完成人)。
代表论文与著作(限第1作者及通讯作者):
1.Zhang X,ZhaoJ,Zhou C,Li W,LiuY,Wei C,Wang Y,Hong X,Zhu XP*,LiuXL*. Assessing andscreening offemalefertility inartificiallybred Asianyellowpondturtles (Mauremys mutica)basedonparentageassignment. Animals.2024, 14:479.
2.Hong X, LiuH, Wang Y,LiM,Ji L, Wang K, Wei C,Li W,Chen C,Yu L,Zhu X*,Liu XL*. A chromosome-level genome assembly of the Asian giant softshell turtlePelochelys cantorii.SciData.2023,10(1):754.
3.Liu XL,Liu H,Wang Y,LiM,Ji L,WangK,Wei C,Li W,Chen C,Yu L, Zhu X*,Hong X*.Chromosome-levelanalysis of thePelochelys cantoriigenomeprovidesinsights toitsimmunity,growth andlongevity. Biology.2023, 12:939.
4.Hong X,Wang Y,Wang Y,Wei C,Li W,Yu L,Xu H,ZhuJ,Zhu X*,LiuXL*.Single-cellatlasreveals thehemocytesubpopulations andstressresponses in Asiangiantsoftshellturtles duringhibernation.Biology.2023, 12:994.
5.Liu XL, Wang Y, Yuan J, Liu F, Hong X, Yu L, Chen C, Li W, Ni W, Liu H, Zhao J, Wei C, Chen H, Liu Y, Zhu X. Chromosome-level genome assembly of Asian yellow pond turtle (Mauremys mutica) with temperature-dependent sex determination system. Sci Rep. 2022,12(1):7905.
6.Liu F, Xu H, Ni W, Wang Y, Hong X, Li W, Yu L, Chen C, Wei C,Liu XL*, Zhu X*. Temporal variation in DNA methylation during gonadal development in a reptile with temperature-dependent sex determination. Biol Reprod. 2022, 107(5): 1217-1227.
7.Liu XL,Liu F,Xu HY,Yang YP,Wang YK,Hong XY,Li W,Yu LY,; Chen C,Xu H,Zhu X*. Characterization of theinvitroculturedovariancells in the Asianyellowpondturtle (Mauremysmutica). Biology.2022, 11:1404.
8.Liu XL, Li W, Yang Y, Chen K, Li Y, Zhu X, Ye H, Xu H*. Transcriptome profiling of the ovarian cells at the single-cell resolution in adult Asian Seabass.Front Cell Dev Biol.2021, 9:647892.
9.Yuan J, Wang YK, Liu F, Li W, Hong XY, Chen C, Yu LY, Ni W, Wei C,Liu XL*, Zhu XP*. Comparative transcriptomic analysis reveals the gonadal development-related gene response to environmental temperature inMauremys mutica. Comp Biochem Physiol Part D Genomics Proteomics.2021, 40:100925.
10.Ni W, Liu Y, Chen HG, Yu LY, Li W, Wang YK, Hong XY, Chen C, Yuan J, Liu F,Liu XL*, Zhu XP*. The complete mitochondrial genome ofPangasianodon hypophthalmus(Sauvage 1878) (Siluriformes, Pangasiidae). Mitochondrial DNA B Resour.2021,6(12):3391-3392.
11.Liu XL, Zhu YY, Zhao YY, Wang YK, Li W, Hong XY, Yu LY, Chen C, Xu H*, Zhu XP*.Vasaexpression is associated with sex differentiation in the Asian yellow pond turtle,Mauremys mutica. J Exp Zool B Mol Dev Evol.2021, 336:431-442.
12.Liu XL#, Zhu YY#, Wang YK, Li W, Hong XY, Zhu XP*, Xu HY*. Comparative transcriptome analysis reveals the sexual dimorphic expression profiles of mRNAs and non-coding RNAs in the Asian yellow pond turtle (Mauremys mutica). Gene.2020, 750: 144756.
13.Liu XL#, Tang ZK#, Zhang PY, Zhu XP, Chu ZJ, Li W, Xu HY*. Identification and characterization ofDAZfamily genes in Chinese soft-shell turtle (Pelodiscus sinensis). J Exp Zool B Mol Dev Evol.2019, 9: 13030-13042.
14.Liu XL#, Li W#, Ye ZY, Zhu YY, Hong XY, Zhu XP*.Morphological characterization and phylogenetic relationships of Indochinese box turtles-theCuora galbinifronscomplex.Ecol Evol. 2019, 9(23):13030-13042.
15.Liu XL, Wang YK, Ouyang S, Zhu YY, Li W, Hong XY, Xu HY*, Zhu XP*. Evolutionary conservation oftransferringenomic organization and expression characterization in seven freshwater turtles.Biochem Biophys Res Commun.2018, 506(4): 874-882.
16.Li X#,Liu XL#, Zhu Y, Zhang J, Ding M, Wang M, Wang Z, Li Z, Zhang X, Zhou L,Gui JF*.Origin and transition of sex determination mechanisms in a gynogenetic hexaploid fish. Heredity.2018, 121: 64-74.
17.Liu XL, Jiang FF, Wang ZW, Li XY, Li Z, Zhang XJ, Chen F, Mao JF, Zhou L, Gui JF*. Wider geographic distribution and higher diversity of hexaploids than tetraploids in Carassius species complex reveal recurrent polyploidy effects on adaptive evolution. Sci Rep.2017, 7: 5395.
18.Liu XL, Li XY, Jiang FF, Wang ZW, Li Z, Zhang XJ, Zhou L, Gui JF*. Numerous mtDNA haplotypes reveal multiple independent polyploidy origins of hexaploids inCarassiusspecies complex.Ecol Evol.2017, 7: 10604-10615.
19.徐昊旸,洪孝友,魏成清,刘毅辉,李伟,朱新平*,刘晓莉*.基于无壳孵化黄喉拟水龟胚胎发育活体观察.水生生物学报, 2023, 47(11):1869-1876.
20.徐昊旸,杨雪莹,倪未,刘芳,陈海港,朱新平*,刘晓莉*.乌龟选育世代遗传多样性及遗传结构的微卫星分析.大连海洋大学学报, 2023, 38(5):812-818.
21.徐昊旸,彭明伟,朱新平*,刘晓莉*.虎纹麝香龟家庭繁养技术.科学养鱼,2023, 09: 026.
22.刘晓莉#,唐舟凯,张飘逸,朱新平,储张杰,李伟,吴栩灵,徐红艳*.中华鳖boule基因在生殖细胞中的表达分析.动物学杂志,2019(1): 66-75.
23.刘晓莉,朱新平.中国龟鳖产业形势与创新发展.珠江水产科学,2018, 9(3): 115-120.