王英英,女,内蒙古呼伦贝尔人,1984年出生,博士,副研究员。在水产病害防控领域,尤其是水生动物细胞生物学方面具有扎实的基础理论和专业技能,针对草鱼呼肠孤病毒、锦鲤疱疹病毒、罗非鱼湖病毒等重要和新发水生动物病原分离鉴定、敏感细胞系的建立、致病机制、疫苗研发等方面开展了细致深入的研究。内容涉及大宗淡水鱼类病毒病分子流行病学、诊断技术、致病机制和免疫防控等领域。主持省广东省自然科学基金等省部级项目3项。作为作为项目秘书和主要骨干参与国家科技支撑项目、国家自然科学基金,现代农业产业技术体系等项目10余项。在国内外期刊发表论文60余篇,其中第一及通讯作者SCI论文9篇。获授权国家发明专利20余项(第一发明人8项);参编著作7部;发布国家标准1项,农业行业标准2项。获江西省科技进步奖二等奖(排名第9)、中国水产科学研究院科学技术进步奖三等奖(排名第4)等。
联系方式:
(1)电话:020-86538302/13710526251
(2)邮箱:wang-dixiaoye2008@163.com
(3)通讯地址:广州荔湾区西朗兴渔路1号
研究方向:
(1)水生动物病毒病防控
(2)水生动物细胞培养
主持的重点项目(列举重大项目5项):
1.广东省自然科学基金,罗湖病毒感染TiBC后MicroRNA表达谱差异性分析及MicroRNA调控机制研究,2018-2021年, 10万,主持;
2.广东省自然科学基金,Ⅱ型草鱼呼肠孤病毒强、弱毒株致病性差异的分子机制研究,2019-2022年,10万,主持;
3.广东省实施标准化战略专项资金项目,鱼类细胞系 第14部分:锦鲤吻端细胞系(KS)(SC/T 7016.13-2019),2021年,5万,主持;
4.水科院基本科研业务费,草鱼出血病细胞灭活疫苗生产关键技术与产品研发,2019-2022年,55万,主持;
5.中国水产科学研究院珠江水产研究所基本科研业务费,罗湖病毒敏感细胞系的建立及应用,2018-2019年,10万,主持。
代表论文与著作(限第1作者及通讯作者):
1.Yingying Wang, Qing Wang, Yingying Li, Jiyuan Yin, Yan Ren, Cunbin Shi,Sven M. Bergmann, Xinping Zhu, Weiwei Zeng.Integrated analysis of mRNA-miRNA expression in Tilapia infected with Tilapia lake virus (TiLV) and identifies primarily immuneresponse genes. Fish and Shellfish Immunology, 2020,( 99): 208–226.
2.Yingying Wang, Zhili Lic, Qing Wang, Weiwei Zeng, Yingying Li, Jiyuan Yin,Sven M. Bergmannd, Xinping Zhu.Establishment of a brain cell line obtained from hybrids of Channa argus×Channa maculata for the detection of tilapia lake virus. Microbial Pathogenesis, 2020, 138: 103810.
3.Yingying Wang, Qing Wang, Weiwei Zeng, Jiyuan Yin, Yingying Li, Yan Ren, Cunbin Shi, Sven M. Bergmann, Xinping Zhu.Establishment and Characterization of a Cell Line from Tilapia Brain for detection of Tilapia Lake Virus. Journal of fish disease, 2018,41:1803-1809.
4.Y Wang,W Zeng, Q Wang, Y Li,S M Bergmann, S Zheng,Y Ren,C Liu,O Chang,P Lee.Establishment and characterization of a new cell line from koi brain (Cyprinus carpio L.).Journal of Fish Disease, 2018,41:357–364.
5.Yingying Wang, Weiwei Zeng, Yingying Li , Hongru Liang, Chun Liu, Houjun Pan, Peiyu Lee, Shuqin Wu, Sven M. Bergmann, Qing Wang. Development and characterization of a cell line from the snout of koi (Cyprinus carpio L.) for detection of koi herpesvirus. Aquaculture,2015, 435: 310–317.
6.Yuru Yang,Yingying Wang*, Qing Wang, Weiwei Zeng , Yingying Li, Jiyuan Yin, Siyu Wu, Cunbin Shi.Establishment of a cell line from swim bladder of the Grass carp(Ctenopharyngodon idellus)for propagation of Grass Carp Reovirus Genotype II.Microbial Pathogenesis ,2021,151 : 104739.
7.Ye Ge, Qiucheng Yao,Yingying Wang*,Qing Wang,Weiwei Zeng. Deep illumine miRNA Sequencing Provides Insights into the Mechanism Underlying Grass Carp Reovirus Infection. Aquaculture Research, 2020, 52(2) : 463-470. (通讯作者)
8.Yahui Wang, Qing Wang, Sven M. Bergmann, Yingying Li, Bo Li, Yuefeng Lv, Jiyuan Yin, Guang Yang, Yang Qv,Yingying Wang*, Weiwei Zeng. Development and comparative evaluation of real-time PCR and real-time RPA assays for detection of tilapia lake virus. Molecular and Cellular Probes, 2021, 101776.
9.Yuefeng Lv,Yingying Wang*, Qing Wang, Yingying Li, Jiyuan Yin, Guang Yang,Cunbin Shi, Bo Li Yahui Wang, Weiwei Zeng*. Establishment and characterization of a new cell line from from rare minnow brain (Gobiocypris rarus). Aquaculture Research,2022, 00, 1– 12.
10.Yingying Wang, Qing Wang, Yingying Li, Jiyuan Yin, Yan Ren, Cunbin Shi, Gobiocypris Rarus Swim Bladder Cell Line And Culture Method And Induced Transformation Method Thereof. Patent No.:2020102488.
11.王英英,王庆,曾伟伟,李莹莹,石存斌,吴淑勤。一种锦鲤脑细胞系的构建方法及其应用。国家发明专利,2020,专利号:ZL201510531300.7.
12.王英英,曾伟伟,王庆,任燕,李莹莹,石存斌,朱新平。罗非鱼脑细胞系及其应用。国家发明专利,2019,专利号:ZL 201810451080.0
13.王英英,王庆,曾伟伟,李莹莹,尹纪元,任燕,常藕琴,石存斌。一株杂交鳢脑细胞系的建立及应用。国家发明专利,2020,专利号:ZL 201910743467.8
14.王英英,王庆,曾伟伟,李莹莹,尹纪元,常藕琴,石存斌.一株乌斑鳢肾细胞系及其构建方法和应用,国家发明专利,2020,专利号ZL201910626036.3.2.
15.王英英,曾伟伟,王庆,吴淑勤,梁红茹,李莹莹,石存斌。一株草鱼鱼鳔上皮样细胞系及其应用.国家发明专利,2016,专利号:ZL 2014 1 0133998.2
16.王英英,王庆,曾伟伟,李凯彬,李莹莹,尹纪元,石存斌.一种剑尾鱼仔鱼细胞系及其构建方法和应用,国家发明专利,2021,专利号ZL201910842355.8
17.王英英,王庆,曾伟伟,李凯彬,李莹莹,尹纪元,石存斌.草鱼呼肠孤病毒II型巢式RT-PCR检测引物组、试剂盒及其应用,国家发明专利,2021,专利号ZL 2020109152965