高风英，女，1976年12月出生，博士，副研究员，毕业于上海海洋大学水产养殖专业，硕士研究生导师，国家特色淡水鱼产业技术体系岗位科学家。主要从事鱼类健康养殖及选育种研究。研究涉及鱼类抗病选育及免疫相关基因的挖掘及功能分析等领域。先后主持国家现代农业产业技术体系项目、国家及省级重点研发计划、国家自然科学基金、广东省自然科学基金、广东省科技计划项目等9项；参与国家科技支撑计划、广东省渔业发展专项等科研项目10余项。近年在国内外期刊公开发表论文近100篇，其中，第1作者及通讯作者35篇（其中SCI论文21篇）。作为骨干获得新品种2个；获发明专利授权5件。获水科院科技进步一等奖1项、二等奖1项，水科院科技进步三等奖1项，水科院大渔创新奖1项，广东省农业技术推广奖2项，范蠡科学技术奖二等奖1项。2013年获得广东省直机关“三八红旗手”荣誉称号。
联系方式：
(1)电话：13662315839
(2)邮箱：fengyinggao2011@163.com
研究方向：鱼类健康养殖及选育种
主持的重点项目（仅列重大项目5项）
1．国家特色淡水鱼产业技术体系专项(CARS-46)：淡水鲈种质资源与品种改良岗位，2023～2025年，210万。
2．国家重点研发计划：罗非鱼抗细菌感染的先天免疫机制(2018YFD0900302-9)，起止时间：2018年12月-2022年12月，46万。
3．国家自然科学基金：尼罗罗非鱼MHC I基因组区域标签SNPs的挖掘及其在辅助抗病育种中的应用潜力探讨(31402295)，起止时间：2015年1月-2017年12月, 25万。
4．广东省自然科学基金：DDX41和Sting基因信号转导机制及其在抵御链球菌感染中的作用研究(2020A1515010883),起止时间：2019年-2022年，10万。
5．广东省科技计划项目：尼罗罗非鱼抗链球菌新品系培育技术研究(2016A020210022)，起止时间：2016年7月-2019年7月，15万。
代表论文（仅列第一作者和通讯作者SCI论文）
1. Junjian Dong, Hetong Zhang, Ziyang Wang, Chengfei Sun,Fengying Gao*, Xing Ye*. High temperature exposure causes sexual dimorphism in immune responses against largemouth bass ranavirus (LMBV) inMicropterus salmoides. Aquaculture 592 (2024) 741239.通讯作者
2.Fengying Gao, Junjian Dong, Jiaxin Li, Zhilin Zhu, Hetong Zhang, Chengfei Sun*, Xing Ye. TLR21 is involved in the NF-κB and IFN-β pathways in largemouth bass (Micropterus salmoides) and interacts with TRIF but not with the Myd88 adaptor. Fish and Shellfish Immunology 151 (2024) 109734.第一作者
3. Qiuyue Zheng, Zhigang Liu, Chengfei Sun, Junjian Dong, Hetong Zhang, Xiaoli Ke*,Fengying Gao*, Maixin Lu. Molecular characterization, expression and functional analysis of TAK1, TAB1 and TAB2 in Nile tilapia (Oreochromis niloticus). Fish and Shellfish Immunology 145 (2024) 109359.通讯作者
4. Junjian Dong, Chengfei Sun, Yuanyuan Tian, Hetong Zhang, Zhigang Liu,Fengying Gao*, Xing Ye*. Genomic organization and gene evolution of two warm temperature acclimation proteins (Wap65s) ofMicropterus salmoidesand their responses to temperature and bacterial/viral infections. International Journal of Biological Macromolecules 227 (2023) 340-353.通讯作者
5. Hetong Zhang, Junjian Dong, Yunyun Yan, Shanshan Liu, Xing Ye,Fengying Gao*and Chengfei Sun*. Development of a Highly Permissive Mandarin Fish (Siniperca chuatsi) Kidney Cell Line for Mandarin Fish Ranavirus Using a Single-Cell Cloning Method. Cells. 2024, 13(1): 18.
6.Gao Feng-ying, Lu Mai-xin*, Wang Miao, Liu Zhi-gang, Ke Xiao-li, Zhang De-feng, Cao Jian-meng.Nile tilapia DNA sensor STING is involved in the IFN-β and AP-1 signaling pathways in the immune response dependent on DDX41. International Journal of Biological Macromolecules 225 (2023) 27-39.第一作者
7. Qiuyue Zheng,Fengying Gao*, Zhigang Liu, Chengfei Sun, Junjian Dong, Hetong Zhang, Xiaoli Ke, Maixin Lu. Nile tilapia TBK1 interacts with STING and TRAF3 and is involved in the IFN-β pathway in the immune response. Fish and Shellfish Immunology 142 (2023) 109125.通讯作者
8.Fengying Gao, Jicai Pang, Maixin Lu*, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao.Nile tilapia TLR3 recruits MyD88 and TRIF as adaptors and is involved in the NF-κB pathway in the immune response.International Journal of Biological Macromolecules 218 (2022) 878–890. IF:8.025.第一作者
9.Fengying Gao,Jicai Pang, Maixin Lu, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao. TLR5 recognizesAeromonas hydrophilaflagellin and interacts with MyD88 in Nile tilapia.Developmental and Comparative Immunology, 2022,133,10409. IF：3.605.第一作者
10.Feng-ying Gao, Xin Zhou, Mai-xin Lu*, Miao Wang, Zhi-gang Liu, Jian-meng Cao, Xiao-li Ke, Meng-meng Yi. Nile tilapia TRIM39 recruits I3K413 and I3KL45 as adaptors and is involved in the NF-κB pathway. Journal of Fish Biology, 2022, 101(1), 144–153 IF:2.504.第一作者
11.Feng-ying Gao,Xin Zhou, Mai-Xin Lu*, Miao Wang, Zhi-Gang Liu, Jian-Meng Cao, Xiao-Li Ke, Meng-Meng Yi, Deng-Gao Qiu.TLR1 in Nile tilapia: The conserved receptor cannot interact with MyD88 and TIRAP but can activate NF-κB in vitro.Developmental and Comparative Immunology, 127 (2022) 104300. IF：3.605.第一作者
12. Xin Zhou,Fengying Gao*, Maixin Lu*, Zhigang Liu, Miao Wang, Jianmeng Cao, Xiaoli Ke, Mengmeng Yi. DDX43 recruits TRIF or IPS-1 as an adaptor and activates the IFN-β pathway in Nile tilapia (Oreochromis niloticus).Molecular Immunology 143 (2022) 7–16.IF：4.174.通讯作者.
13.Fengying Gao, Jie Liu, Maixin Lu*, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao. Nile tilapia Toll-like receptor 7 subfamily Intracellular TLRs that recruit MyD88 as an adaptor and activate the NF-κB pathway in the immune response. Developmental Comparative Immunololgy 2021, 125:104173. IF：3.636.第一作者
14.Gao Feng-ying, Pang Ji-cai, Wang Miao, Lu Mai-xin, Liu Zhi-gang, Cao Jian-meng, Ke Xiao-li, Yi Meng-meng. Structurally diverse genes encode TLR13 in Nile tilapia: The two receptors can recognize Streptococcus 23S RNA and conduct signal transduction through MyD88. Molecular Immunology, 2021, 132,60-78. IF：4.407.第一作者
15. Xueqing Han,Fengying Gao*, Maixin Lu*, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao. Molecular characterization, expression and functional analysis of IRAK1 and IRAK4 in Nile tilapia (Oreochromis niloticus). Fish & Shellfish Immunology, 2020, 97: 135–145. SCI，IF：3.29.通讯作者
16. Xue-qing Han,Fengying Gao*, Maixin Lu*, Zhig-ang Liu, Miao Wang, Xiao-li Ke, Yan-xia Gao. Identification and characterization of tumor necrosis factor receptor (TNFR)-associated factor 3 from Nile tilapia,Oreochromis niloticus. Journal of fish biology, 2020, 96(1):185-193. SCI，IF：2.04 .通讯作者
17.Feng-Ying Gao,Dong Zhang, Mai-Xin Lu*, Jian-Meng Cao, Zhi-Gang Liu, Xiao-Li Ke, Miao Wang, De-Feng Zhang. MHC Class IIB gene polymorphisms associated with resistance/susceptibility to Streptococcus agalactiae in Nile tilapiaOreochromis niloticus. DISEASES OF AQUATIC ORGANISMS, 2019, 133: 253–261. IF=1.659，第一作者
18.Feng-Ying Gao,Dong Zhang, Mai-Xin Lu*, Jian-Meng Cao, Zhi-Gang Liu, Xiao-Li Ke, Miao Wang, De-Feng Zhang, Meng-Meng Yi. MHC class IIA polymorphisms and their association with resistance-susceptibility toStreptococcus agalactiaein Nile tilapia,Oreochromis niloticus. Journal of Fish Biology. 2018; 93:1207-1215. SCI，IF：1.79.第一作者
19.Feng-Ying Gao,Mai-Xin Lu*, Miao Wang, Zhi-Gang Liu, Xiao-Li Ke, De-Feng Zhang, Jian-Meng Cao. Molecular characterization and function analysis of three RIG-I-like receptor signaling pathway genes (MDA5, LGP2 and MAVS) inOreochromis niloticus. Fish and Shellfish Immunology 82 (2018) 101–114. SCI, IF:3.18,第一作者
20.Feng-ying Gao,Ji-cai Pang, Mai-xin Lu*, Xian-le Yang*, Hua-ping Zhu, Xiao-li Ke, Zhi-gang Liu, Jian-meng Cao, Miao Wang. Molecular characterization, expression and functional analysis of NOD1, NOD2 and NLRC3 in Nile tilapia (Oreochromis niloticus). Fish & Shellfish Immunology, 2018,73:207-219. SCI, IF:3.18第一作者
21. Ji-cai Pang1,Feng-ying Gao1, Mai-xin Lu*, Xing Ye, Hua-ping Zhu, Xiao-li Ke. Major histocompatibility complex class IIA and IIB genes of Nile tilapiaOreochromis niloticus: Genomic structure, molecular polymorphism and expression patterns. Fish & Shellfish Immunology, 2013, 34 (2):486-496，SCI, IF:3.32,共同第一作者
