
姓名:李伟
职称/职务:副研究员/副主任
学历、学位:研究生、博士
联系电话:15013083966
电子邮件:664061430@qq.com
个人简介:
1984年出生,山东聊城人,博士,副研究员,硕士生导师,获“珠江科技新星”人才称号。本科毕业于山东大学生物科学专业,硕士毕业于华东师范大学生态学专业,博士毕业于上海海洋大学水产养殖专业。
现任水产种质资源与遗传育种研究室副主任,中国水产科学研究院“龟鳖遗传育种创新团队”首席,中国水产科学研究院学术委员会委员,长期从事水产动物种质资源与遗传育种的研究工作,研究涉及生态学、分子生物学、细胞生物学、生物信息学等领域。
主持国家自然科学基金、国家重点研发计划水产生物育种共性前沿技术创新青年科学家项目(子课题)、农业基础性长期性科技工作国家渔业科学数据中心观测监测任务、广东省自然科学基金面上项目、广州市科技计划科技创新人才专项、中国水产科学研究院院级基本科研业务费等项目共20余项。作为主完成人,获新品种1个;获得成果奖励3项;发表论文60余篇(第一作者/通讯作者26篇);授权发明专利20余项(第一发明人9项)、实用新型专利10余项(第一发明人1项);参编著作3部;主笔撰写五华县养殖水域滩涂规划;为广东省首例违法捕鱼生态补偿案件提供参考意见报告;为佛山市南海区、顺德区的渔业资源调查及增殖放流等提供方案及建议2份。
研究方向:
1.水产动物种质资源评价与保护(龟鳖类、名特优鱼类)
2.水产动物遗传资源开发与利用(龟鳖类、名特优鱼类)
3.水产动物遗传育种与健康养殖(龟鳖类、名特优鱼类)
4.两栖爬行类基础生物学研究
5.濒危水生动物保育与拯救
社会兼职:
兼任“第十届广东省海洋湖沼学会”、“第九届广东海洋学会”理事,中国水产流通与加工协会“龟鳖行业专家技术委员会”委员。
高校校外导师兼职情况:
上海海洋大学、西南大学、陕西理工大学、长江大学、江苏海洋大学、河南师范大学、福建农林大学、新疆农业大学及天津农学院等高校的硕士生导师。
获奖情况:
1.茂名市科学技术奖一等奖(2017年)
2.钟麟水产种业科技奖(2022年)
3.全国龟鳖行业科技创新特等奖(2023年)
近几年代表性论文及其他代表性成果(限第1作者及通讯作者):
1.Ji L#, Shangguan Y, Chen C, Wei C, Zhu J, Hong X, Liu X, Zhu X, Li W*. Dietary Tannic Acid Promotes Growth Performance and Resistance Against Aeromonas hydrophila Infection by Improving the Antioxidative Capacity and Intestinal Health in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis). Antioxidants (Basel). 2025 Jan 20;14(1):112. doi: 10.3390/antiox14010112. PMID: 39857447; PMCID: PMC11759827.(IF2023=6.0,JCR一区)
2.Ji L#, Shi Q, Chen C, Liu X, Zhu J, Hong X, Wei C, Zhu X, Li W*. Biochemical, Histological, and Multi-Omics Analyses Reveal the Molecular and Metabolic Mechanisms of Cold Stress Response in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis). Biology (Basel). 2025 Jan 11;14(1):55. doi: 10.3390/biology14010055. PMID: 39857286; PMCID: PMC11760877.2 (IF2023=3.6,JCR一区)
3.Liu P#, Liu Y, Zhu J, Chen C, Ji L, Liu X, Hong X, Wei C, Zhu X, Xu Q, Zhou J, Li W*. Sex-Dimorphic Differential Expression Profiles in the Brain of the Adult Chinese Soft-Shelled Turtle, Pelodiscus sinensis. Animals (Basel). 2024 Nov 27;14(23):3426. doi: 10.3390/ani14233426. PMID: 39682392; PMCID: PMC11640296. (IF2023=2.7,JCR一区)
4.Liqin Ji#, Chen Chen, Junxian Zhu, Xiaoyou Hong, Xiaoli Liu, Chengqing Wei, Xinping Zhu*, and Wei Li*. Integrated time-series biochemical, transcriptomic, and metabolomic analyses reveal key metabolites and signaling pathways in the liver of the Chinese soft-shelled turtle (Pelodiscus sinensis) against Aeromonas hydrophila infection. Frontiers in Immunology. 2024, 15:1376860. (IF2023=5.7,JCR一区)
5.Junxian Zhu, Yongchang Wang, Chen Chen, Liqin Ji, Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu*, and Wei Li*. Identification of sex-specific markers and candidate genes using WGS sequencing reveals a ZW-type sex-determination system in the Chinese soft-shell turtle (Pelodiscus sinensis). International Journal of Molecular Sciences. 2024, 25, 819. (IF2023=4.9,JCR一区)
6.Yongchang Wang, Junxian Zhu, Chen Chen, Liqin Ji, Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu, Junjie Zhang*, and Wei Li *(2024), Whole-Genome Identification and Characterization of the DKK Gene Family and Its Transcription Profiles: An Analysis of the Chinese Soft-Shell Turtle (Pelodiscus sinensis). Animals, 2024, 14(6): 931. doi: 10.3390/ani14060931.(IF2023=2.7, JCR一区)
7.Junxian Zhu, Pan Liu, Liqin Ji, Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu, Chen Chen*, and Wei Li*. Development and characterization of 68 SNPs markers in the critically endangered species, Palea steindachneri. Conservation Genetics Resources. 2024. (IF2023=0.9,JCR三区)
8.Junxian Zhu Yongchang Wang, Luo Lei, Chen Chen, Liqin Ji, Jiansong Li, Congcong Wu, Wenjun Yu, Laifu Luo, Weiqin Chen, Pan Liu, Xiaoyou Hong, Xiaoli Liu, Haigang Chen, Chengqing Wei, Xinping Zhu*, and Wei Li*. Comparative genomic survey and functional analysis of DKKL1 during spermatogenesis in the Chinese soft-shelled turtle (Pelodiscus sinensis). Int J Biol Macromol. 2023, 30:127696. (IF2022=8.2, 中科院一区)
9.Junxian Zhu, Luo Lei, Chen Chen, Jiansong Li, Yongchang Wang, Congcong Wu, Yakun Wang, Xiaoyou Hong, Xiaoli Liu, Lingyun Yu, Haigang Chen, Chengqing Wei, Yihui Liu, Wei Li*, and Xinping Zhu* (2023), Development and evaluation of a medium-free incubation method for hatching Chinese soft-shelled turtle (Pelodiscus sinensis) eggs. Aquacult Rep. 31: 2352-5134. doi: https://doi.org/10.1016/j.aqrep.2023.101643. (IF2022=3.7, JCR一区)
10.Lei Luo, Zhu Junxian, Chen Chen, Wang Yongchang, Wu Congcong, Qi Ming,Wang Yakun, Liu Xiaoli, Hong Xiaoyou, Yu Lingyun, Chen Haigang, Wei Chengqing,Liu Yihui, Li Wei* and Zhu Xinping* (2023), Genome-wide identification, evolution and expression analysis of bone morphogenetic protein (BMP) gene family in chinese soft-shell turtle (Pelodiscus sinensis). Front. Genet. 14:1109478.doi: 10.3389/fgene.2023.1109478(IF2021=4.772, JCR一区)
11.Junxian Zhu#, Luo Lei#, Chen Chen, Yakun Wang, Xiaoli Liu, Lulu Geng, Ruiyang Li, Haigang Chen, Xiaoyou Hong, Lingyun Yu, Chengqing Wei, Wei Li*, Xinping Zhu*. Whole-Transcriptome Analysis Identifies Gender Dimorphic Expressions of Mrnas and Non-Coding Rnas in Chinese Soft-Shell Turtle (Pelodiscus sinensis). Biology. 2022 11, 834. Doi.org/10.3390/biology11060834 (IF2021=5.168, JCR一区)
12.Luo Lei#, Junxian Zhu#, Chen Chen, Yakun Wang, Xiaoyou Hong, Xiaoli Liu, Lingyun Yu, Chengqing Wei, Haigang Chen, Yihui Liu, Ruiyang Li, Wei Li*, Xinping Zhu*, Expression and Characterization of the Spats1 Gene and Its Response to E2/MT Treatment in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis). Animals 2022, 12, 1858.https://doi.org/10.3390/ (IF2021=3.231, JCR一区)
13.Luo Lei#, Chen Chen, Junxian Zhu, Yakun Wang, Xiaoli Liu, Haiyang Liu, Lulu Geng, Junyu Su, Wei Li*, Xinping Zhu*, Transcriptome analysis reveals key genes and pathways related to sex differentiation in the Chinese soft-shelled turtle (Pelodiscus sinensis). Comp Biochem Physiol Part D Genomics Proteomics. 2022, 42: 100986. (IF2021=3.306, JCR三区)
14.Wei Li#, Junxian Zhu, Luo Lei, Chen Chen, Xiaoli Liu, Yakun Wang, Xiaoyou Hong, Lingyun Yu, Hongyan Xu *, Xinping Zhu*, The Seasonal and Stage-Specific Expression Patterns of HMGB2 Suggest Its Key Role in Spermatogenesis in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis). Biochemical Genetics, 2022: 1-14. (IF2021=2.220, JCR四区)
15.Wei Li#, Junxian Zhu, Chen Chen, Yakun Wang, Luo Lei, Lulu Geng, Junyu Su ,Xinping Zhu*, Isolation and characterization of sex‐linked SNP markers from transcriptomic sequences of the Chinese soft‐shelled turtle (Pelodiscus sinensis)[J]. Conservation Genetics Resources, 2022: 1-6. (IF2021=0.991, JCR四区)
16.Wei Li#, Luo Lei, Junxian Zhu, Haigang Chen, Chen Chen, Yakun Wang, Lulu Geng, Fangcan Chen, Xinping Zhu*, Simple and rapid method for molecular identification of Konosirus punctatus and Clupanodon thrissa[J]. Conservation Genetics Resources, 2022: 1-3. (IF2021=0.991, JCR四区)
17.Yakun Wang#, Xiaoli Liu, Lingyun Yu, Xiaoyou Hong, Jian Zhao, Junxian Zhu, Ju Yuan, Wei Li*, Xinping Zhu*, Identification and analysis of novel microRNAs provide insights to reproductive capacity of the cultured Asian yellow pond turtle Mauremys mutica[J]. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2021, 40: 100890. (IF2021=3.306, JCR三区)
18.Liu Xiaoli#, Li Wei#, Ye Zhaoyang, Zhu Yanyu, Hong Xiaoyou, Zhu Xinping*. Morphological characterization and phylogenetic relationships of Indochinese box turtles—The Cuora galbinifrons complex. Ecology and Evolution, 2019, 23(9): 13030-13042. (IF2021=3.167, JCR三区)
19.Wei Li#, Piaoyi Zhang#, Xuling Wu, Xinping Zhu*, Hongyan Xu*, A Novel Dynamic Expression of vasa in Male Germ Cells during Spermatogenesis in the Chinese Soft-Shell Turtle (Pelidiscus sinensis), Journal of Experimental Zoology Part B Molecular & Developmental Evolution, 2017, 328(3):230-239.(封面论文) (IF2021=2.368, JCR一区)
20.Wei Li#, Xincheng Zhang, Jian Zhao, Yan Shi, Xinping Zhu*, Complete mitochondrial genome of Cuora trifasciata (Chinese three-striped box turtle), and a comparative analysis with other box turtles, Gene, 2015, 555(2): 169-77. (IF2021=3.913, JCR二区)
21.Wei Li#, Jian Zhao, Yan Shi, Feng-Fang Xiao, Xin-Cheng Zhang , Xin-Ping Zhu*,The complete mitochondrial genome of the critically endangered Vietnamese three-striped box turtle (Testudines: Geoemydidae).Mitochondrial Dna, 2015, 26(6):925 (IF2021=0.922, JCR三区)
22.汪泳昌,祝骏贤,李建松,陈 辰,纪利芹,洪孝友,刘晓莉,王亚坤,吴聪聪,余汶君,罗来福,陈海港,魏成清,朱新平,张俊杰*,李 伟*. 中华鳖Dkkl1基因的分子特征及对外源性激素处理的响应[J]. 南方水产科学,2023.
23.雷骆,祝骏贤,陈辰,王亚坤,刘晓莉,洪孝友,于凌云,魏成清,李伟*,朱新平*. 基于转录组测序的中华鳖SSR和SNP特征分析及性别标记筛选[J]. 广东海洋大学学报,2023,43(1):44-49.
24.祝骏贤#,陈辰,刘晓莉,王亚坤,雷骆,洪孝友,于凌云,徐红艳,李伟*, 朱新平*, 中华鳖组蛋白H2A变体克隆及其在卵母细胞中的表达分析[J]. 水生生物学报,2021,45(6):7.
25.李伟#, 史燕, 赵建, 洪孝友, 朱新平*, 中华鳖转铁蛋白基因序列特征及表达研究,水生生物学报, 2015, 39(3):482-489.
26.李伟#, 朱阿莉, 史燕, 朱新平*, 嗜水气单胞菌诱导的中华鳖smart cdna文库构建及相关基因的鉴定, 基因组学与应用生物学,2014, 33(4):788-795.
专利
1.李伟,祝骏贤,朱新平,陈杰湖,陈辰,纪利芹,刘晓莉,洪孝友,魏成清,适用于ZW/XY性别决定系统的性别特异标记检测方法,国家发明专利,专利号:ZL 2024 1 0006784.2,授权日期:2024.09.24
2.李伟,朱新平,雷洛,祝骏贤,陈辰,刘晓莉,洪孝友,纪利芹,汪永昌,鉴别绦虫Testudotaenia sp.WL‑2016的分子标记及应用,国家发明专利,专利号:ZL202310232583.X,授权日期:2024.03.12
3.李伟,朱新平,祝骏贤,陈辰,洪孝友,刘晓莉,纪利芹,雷骆,汪永昌,一种中华鳖精子特异表达分子标记及其应用,国家发明专利,专利号:ZL202310860495.4,授权日期:2024.02.13.
4.李伟,朱新平,雷骆,祝骏贤,陈辰,刘晓莉,洪孝友,纪利芹,汪永昌,一种中华鳖雌性特异Rab35基因及其应用,国家发明专利,专利号:ZL202310860496.9,授权时间:2023.12.12.
5.李伟,祝骏贤,朱新平,雷骆,陈辰,王亚坤,陈海港,洪孝友,刘晓莉,于凌云,刘毅辉,魏成清,鉴别珍珠鳖性别的分子标记、引物对及其应用,国家发明专利,专利号:ZL202211412201.3,授权时间:2023.10.17.
6.李伟,雷骆,朱新平,祝骏贤,陈辰,王亚坤,陈海港,洪孝友,刘晓莉,于凌云,刘毅辉,魏成清,鉴别山瑞鳖性别的分子标记、引物对及其应用,国家发明专利,专利号:ZL202211411732.0,授权时间:2023.08.01.
7.李伟,雷骆,朱新平,祝骏贤,陈辰,王亚坤,陈海港,洪孝友,刘晓莉,于凌云,刘毅辉,魏成清,鉴别角鳖性别的分子标记、引物对及其应用,国家发明专利,专利号:ZL202211411167.8,授权时间:2023.07.04.
8.李伟,朱新平,刘海涌,陈辰,高柳玲,陈海港,陈强,刘毅辉,陈运新,王亚坤,洪孝友,刘晓莉,于凌云,魏成清,一种斑鳠养殖池塘越冬设备,实用新型专利,专利号:ZL202221900204.7,授权时间:2022.10.18.
9.李伟,朱新平,雷骆,陈海港,一种基于线粒体COI基因鉴别花鰶和斑鰶的分子标记及其应用,国家发明专利,专利号:202011419113.7,授权时间:2021.07.03.
10.李伟,朱新平,徐红艳,赵建,陈辰,一种快速鉴定中华鳖遗传性别的PCR扩增引物、方法及试剂盒,国家发明专利,专利号:201810685968.0,授权时间:2020.05.05.