王庆,女,1976年出生,研究室主任,博士,研究员,博士生导师,院百名科技英才。联合国粮食及农业组织(FAO)水产养殖抗微生物药物耐药性和生物安保参考中心主任、广东省水产动物免疫与绿色养殖重点实验室副主任、农业农村部国家水生动物疫病监测计划草鱼出血病首席专家、第三届农业农村部水产养殖病害防治专家委员会委员、第六届全国水产标准化技术委员会委员、第一届水产养殖病害防治分技术委员会委员、中国水产学会鱼病专业委员会委员、广东省现代农业产业技术体系创新团队疫病防控岗位专家。主要从事水产动物病害防控技术研究,以草鱼出血病等淡水鱼重要病害为研究对象,系统开展了流行病学、诊断技术、致病机制、疫苗创制、生态防控等方面的研究。主持国家自然科学基金、国家科技支撑计划子课题、国家重点研发项目子课题、动物疫情监测与防治(渔业)项目、广东省科技计划重点项目(产业化类别)、广东省财政鱼病防治专项、水产行业标准、广州市科技计划重点研发项目共计30余项,参与农业公益性行业科研专项、国家科技支撑计划、现代农业产业技术体系、农业部948计划等项目20余项。获得省科技进步二等奖1项、范蠡科技进步二等奖1项、水科院科技进步二等奖和三等奖各1项、岭南动植物科学技术奖一等奖1项。发表论文90余篇,其中SCI 40余篇,授权国家发明专利17项,制定国家及行业标准5项。参与编写专著11本,指导培养研究生27名。2011年入选水科院“百名科技英才人选”,2013-2015年分别通过德国DAAD奖学金、中国外专局项目全额资助赴德国动物健康研究院病原学研究所进行培训和学习,2015年-2016通过国家留学基金委资助赴美国俄勒冈州立大学兽医学院进行为期一年的访问学习。目前为上海海洋大学博士生导师,华南农业大学、西南大学、天津农学院、盐城工学院等学术型硕士生导师。
联系方式:
(1)电话:020-86538320/13450438588
(2)邮箱:wangqing@prfri.ac.cn
(3)通讯地址:广州荔湾区西朗兴渔路1号
研究方向:水产病害防治
主持的重点项目:
1.国家自然科学基金项目:基因II型草鱼呼肠孤病毒预测表面纤突与连接粘附分子GcJAM-A的相互作用研究(31602202,2017-2019年),19万,主持;
2.广东省科技计划重点项目:草鱼出血病二价灭活疫苗的研制与应用示范(2016B090918115,2016-2018年),100万,主持;
3.广东省省级促进经济发展专项资金(海洋经济发展用途)项目:基于芽孢杆菌呈递系统的鱼类新型疫苗研究及应用(2019-2021年),100万,主持;
4.农业部财政项目:动物疫情监测与防治(渔业)项目-草鱼出血病风险评估(2022-2024),63万,主持;
5.广东省重点领域研发计划项目:养殖鱼类重要疾病安全高效疫苗研发和示范(2011-2016),80万,课题主持;
6.广州市科技计划重点研发项目:草鱼出血病快速诊断和预警关键技术研究与应用(2024-2026),50万,主持。
代表论文与著作(限第1作者及通讯作者)
1. Huiliang Wu, Jiyuan Yin, Siming Li, Hao Wang, Peng Jiang, Pengfei Li, Zhaoyang Ding, Han Yan, Bo Chen, Linchuan Wang,Qing Wang*. Oral immunization with recombinantL. lactisexpressing GCRV-II VP4 produces protection against grass carp reovirus infection.Fish and Shellfish Immunology,2024, 147, 109439.
2. Yingying Wang, Shucheng Zheng, Weiwei Zeng, Jiyuan Yin, Yingying Li, Yan Ren, Xubing Mo, Cunbin Shi, Sven M. Bergmann,Qing Wang*. Comparative transcriptional analysis between virulent isolate HN1307 and avirulent isolate GD1108 of grass carp reovirus genotype II.Developmental and Comparative Immunology, 2023, 147, 104893.
3. Nan Wang, Jiahao Li, Yajun Wang, Yingying Wang, Defeng Zhang, Cunbin Shi, Yingying Li, Sven M. Bergmann, Xubing Mo, Jiyuan Yin*,Qing Wang*Recombinant Lactococcus lactis expressing grass carp reovirus VP6 induces mucosal immunity against grass carp reovirus infection.Frontiers in Immunology, 2022,13, 914010.
4. Caixia Gao, Yingying Wang, Huzi Hu, Wenli Zhou, Jiyuan Yin, Yingying Li, Sven M. Bergmann, Siyu Wu, Weiwei Zeng,Qing Wang*. Assessment of a natural grass carp reovirus genotype II avirulent strain GD1108 shows great potential as an avirulent live vaccine.Microbial Pathogenesis,2021,152, 104602.
5. Jiaming Chen, Ouqin Chang, Yingying Li, Yingying Wang, Chao Liu, Jiyuan Yin, Sven M. Bergmann, Weiwei Zeng,Qing Wang*. Establishment of a rare minnow (Gobiocypris rarus) disease model for grass carp reovirus genotype II.Aquaculture, 2021,533, 736133
6. Ting Gao, Caixia Gao, Siyu Wu, Yingying Wang, Jiyuan Yin, Yingying Li, Weiwei Zeng, Sven M. Bergmann andQing Wang*. Recombinant Baculovirus-Produced Grass Carp Reovirus Virus-Like Particles as Vaccine Candidate that Provides Protective Immunity against GCRV Genotype II Infection in Grass Carp.Vaccines, 2021, 9, 53
7.Yuru Yang, Yingying Wang*,Qing Wang**, Weiwei Zeng , Yingying Li, Jiyuan Yin, Siyu Wu, Cunbin Shi. Establishment of a cell linefrom swim bladder of the Grass carp (Ctenopharyngodon idellus) for propagation of Grass carp reovirus genotype II.Microbial Pathogenesis, 2021,151,104739.
8. Zhishen Huang, Yingying Wang, Siyu Wu, Jiyuan Yin, Wenli Zhou, Ting Gao, Yingying Li, Sven M. Bergmann, Caixia Gao, Yahui Wang, Weiwei Zeng,Qing Wang*. An iTRAQ-based comparative proteomic analysis of grass carp infected with virulent and avirulent isolates of grass carp reovirus genotype II.Aquaculture, 2021, 535: 736426.
9. Jiaming Chen, Yingying Li , Yingying Wang, Siyu Wu, Ouqin Chang, Jiyuan Yin, Weiwei Zeng, Sven M. Bergmann,Qing Wang*. Establishment of a rare minnow (Gobiocypris rarus) model for evaluation of experimental vaccines against a disease induced by grass carp reovirus genotype II.Fish and Shellfish Immunology,2021, 117, 53-61
10. Shixu Liu,Qing Wang*, Yingying Wang, Jiaming Chen, Ouqin Chang, Weiwei Zeng, Sven M. Bergmann, Yingying Li, Jiyuan Yin, Hong Wen. Establishment of a cell line from egg of rare minnow Gobiocypris rarus for propagation of grass carp reovirus genotype II.Microbial Pathogenesis, 2019, 136:103715.
11.Qing Wang, Hualiang Xie, Weiwei Zeng*, Linchuan Wang, Chun Liu, Jiexing Wu,Yingying Wang, Yingying Li, Sven M. Bergmann. Development of indirect immunofluorescence assay for TCID50 measurement of grass carp reovirus genotype II without cytopathic effect onto cells.Microbial Pathogenesis, 2018, 114: 68–74