The Laboratory of Aquatic Disease Control and Prevention (Laboratory of Aquatic Laboratory Animal) was established in 1953. Targeting at the serious damage induced by grass carp hemorrhagic disease, traditional immunotherapies were developed in late 1960s and continually being refined, which created a new era of fish infectious disease management in China. It is the first succeeded in developing the live-attenuated vaccine against grass carp hemorrhagic disease, which significantly improved the protection rate and duration and obtained a Registration Certificate of New Veterinary Drugs (1stClass) and the first production certificate for aquatic vaccines in China in 2011. After more than 2 decades of efforts, China’s first aquatic laboratory animal, the swordtail fish, was created and regarded as the aquatic mouse. The swordtail fish strain RR-B has been recognized by the National Appraisal Committee of Aquatic Protospecies and Improved Varieties, therefore emerged a new academic discipline of aquatic laboratory animal in China.
The lab consists of 26 in-service staffs, including 14 professors/associate professors, 12 assistant professors. 1 doctoral and 11 master’s supervisors were appointed. By January 2018, 8 doctoral candidates had been entitle with PhD degree and over 60 master candidates graduated. It is equipped with 18 sets of instruments such as transmission electron microscope, laser confocal microscope, mass spectrometer (liquid chromatography-triple quadrupole mass spectrometer), digital PCR instrument, quantitative fluorescence PCR, ultracentrifuge, automatic nucleic acid extraction workstation, automatic biochemical analyzer, fully automated microbial identification and drug susceptibility analyzer, fully automated western blotting system, macromolecular interaction analysis system, protein purifier, flow cytometry, live cell station, cellular metabolism analyzer, and parallel bioreactor for cell culture.
Research scope:
1. Epidemiological investigation and risk assessment of aquatic animal diseases
2. Interaction mechanism between pathogens and hosts in aquatic animals
3. Aquatic vaccine R&D and immune management
4. Safe use of fishery drugs
5. Aquatic model organisms and related application
6. Microecological preparation R&D and eco-management
7. Aquatic animal disease control and prevention in regions
